In Season 16, it’s a challenge for Ronald “Mac” MacDonald (Rob McElhenney), Charlie Kelly (Charlie Day), Dennis Reynolds (Glenn Howerton), Dee Reynolds (Kaitlin Olson), and Frank Reynolds (Danny DeVito) who yearn for the past as they attempt to survive in 2023. This year alone, Mac battles with allergies and long-distance dating, Charlie takes on his long-forgotten sisters, Dee fights for rent control and women’s athletics, Frank wrestles for his gun, and Dennis struggles to improve his mental health. At the end of the day, they’re navigating 2023 with 16 years of baggage as a few figures from their past rear their heads.
本剧讲述了一个言行不同寻常、不擅长沟通的怪咖医学天才陈辉，进入医院后，亲历复杂的医患关系，面对生命的无常，屡屡受挫，在外科同僚们的帮助下，一步步突破自己"只见疾病不见人"的局限，成长为一名既可以医人也可以医心的好医生。
